Sheryl Lynn Lee (born April 22, 1967) is a German-born American film, stage, and television actress. After studying acting in college, Lee relocated to Seattle, Washington to work in theater, where she was cast by David Lynch as Laura Palmer and Maddy Ferguson on the 1990 cult TV series Twin Peaks and in the 1992 film Twin Peaks: Fire Walk with Me. After completing Twin Peaks, she returned to theater, appearing in the title role of Salome on Broadway opposite Al Pacino.

Her film roles include as Astrid Kirchherr in Backbeat (1994), as well as a lead role in the drama Mother Night (1996), the role of Katrina in John Carpenter's Vampires (1998) and the part of April in Winter's Bone (2010). She has had recurring roles on such television series as One Tree Hill (2005–2006) and Dirty Sexy Money (2007–2009). She reprised her role of Laura Palmer in the Showtime revival of Twin Peaks (2017).