Marie Tifo (French pronunciation: ​[maʁi tifo]; born September 26, 1949 in Jonquière, Quebec) is a Canadian actress, and a major star in French-speaking Canada. She won a Genie Award for Best Performance by an Actress in a Leading Role for her performance in the 1980 drama film Good Riddance (Les Bons débarras). She starred in La Déraison d'amour at the Théâtre du Nouveau Monde in Montreal from 2–13 June 2009.

Tifo played beatified nun Marie de l'Incarnation in the play from a script written by filmmaker Jean-Daniel Lafond for his film Folle de Dieu (Madwoman of God). This stage biography of Marie Guyard, a widowed mother who crossed the Atlantic to establish the Ursuline order of nuns, had premiered that past fall in Quebec City as part of the 400th anniversary celebrations, then toured France. Lafond's film, Folle de Dieu, also starred Tifo, and premiered in Quebec City in 2008.