Ione Skye Lee (; née Ione Skye Leitch, September 4, 1970) is a British-American actress, author, and painter. She made her film debut in the thriller River's Edge (1986) before gaining mainstream exposure for her starring role in Cameron Crowe's Say Anything... (1989). She continued to appear in films throughout the 1990s, with notable roles in Wayne's World (1992), One Night Stand (1997), and But I'm a Cheerleader (1999).

Other film credits include the comedy Fever Pitch (2005) and an uncredited role in Zodiac (2007). Skye also guest-starred on several television series, including The Twilight Zone (2002), Private Practice, and a recurring role on Arrested Development.

In addition to acting, Skye also works as a painter, and has authored several children's books. In 2006, VH1 ranked her number 84 on its list of the 100 Greatest Teen Stars.